English
norskBlar i forfatter "Skjeldestad, Finn Egil"
Viser treff 1-20 av 44
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13-Type HPV DNA Test versus 5-Type HPV mRNA Test in Triage of Women Aged 25–33 Years with Minor Cytological Abnormalities–6 Years of Follow-Up
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-25)Background: A specific, cost-effective triage test for minor cytological abnormalities is essential for cervical cancer screening among younger women to reduce overmanagement and unnecessary healthcare utilization. We compared the triage performance of one 13-type human papillomavirus (HPV) DNA test and one 5-type HPV mRNA test. Methods: We included 4115 women aged 25–33 years with a screening ... -
5-type HPV mRNA versus 14-type HPV DNA test: test performance, over-diagnosis and overtreatment in triage of women with minor cervical lesions
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-07) -
Assessing the association of oxytocin augmentation with obstetric anal sphincter injury in nulliparous women: A population-based, case-control study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Can oxytocin augmentation modify the risk of epidural analgesia by maternal age in cesarean sections?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-07)<p><i>Introduction</i>: Maternal age is an established risk factor for cesarean section; epidural analgesia and oxytocin augmentation may modify this association. We investigated the effects and interactions of oxytocin augmentation, epidural analgesia and maternal age on the risk of cesarean section.</p> <p><i>Material and methods</i>: In all, 416 386 nulliparous women with spontaneous onset of ... -
Changed definition of disease and broader screening criteria had little impact on prevalence of gestational diabetes mellitus
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-26)Introduction - There are major controversies in screening for gestational diabetes mellitus (GDM). The present study evaluates the impact of the 2017 revised guidelines for GDM screening and a changed definition of GDM in Norway.<p> <p>Material and methods - We used a case-series design and included women with no pre-pregnancy diabetes mellitus, who gave birth after gestational week 29 to a ... -
Changes in cesarean section rates after introduction of a punitive financial policy in Georgia: A population-based registry study 2017-2019
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-19)Background<p> <p>There is little research on how financial incentives and penalties impact national cesarean section rates. In January 2018, Georgia introduced a national cesarean section reduction policy, which imposes a financial penalty on hospitals that do not meet their reduction targets. The aim of this study was to assess the impact of this policy on cesarean section rates, subgroups of ... -
Changes in maternal risk factors and their association with changes in cesarean sections in Norway between 1999 and 2016: A descriptive population-based registry study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-03)Background - Increases in the proportion of the population with increased likelihood of cesarean section (CS) have been postulated as a driving force behind the rise in CS rates worldwide. The aim of the study was to assess if changes in selected maternal risk factors for CS are associated with changes in CS births from 1999 to 2016 in Norway.<p> <p>Methods and findings - This national ... -
Cost of unintended pregnancy in Norway: a role for long-acting reversible contraception
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014-12-23) -
Decreasing trends in number of depot medroxyprogesterone acetate starters in Norway - a cross-sectional study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-20)<i>Introduction - </i>In this study, we examined changes in depot medroxyprogesterone acetate (DMPA) prescriptions over a time‐period when new professions started prescribing, and when the method gained some negative media attention.<br><br> <i>Material and methods - </i>The Norwegian Prescription Database provided data on hormonal contraception from 2006 through 2012. We estimated the annual number ... -
Do Norwegian providers comply with national recommendations when prescribing combined oral contraceptives to starters? A cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-26)<i>Objectives</i> - To assess whether changes in patterns of combined oral contraceptive (COC) prescriptions to starters between 2008 and 2016 were in line with changes in national recommendations for use.<p> <p><i>Design</i> - Historical prospective cohort study.<p> <p><i>Setting</i> - The national Norwegian Prescription Database.<p> <p><i>Participants</i> - Women aged 10–49 years who ... -
Ecological study on the use of hormonal contraception, abortions and births among teenagers in the Nordic countries
(Journal article; Peer reviewed, 2018-10-30)Objectives <br>Compare hormonal contraceptive use, birth and abortion rates among teenagers in the Nordic countries. A secondary aim was to explore plausible explanations for possible differences between countries.<br> Design <br> Ecological study using national registry data concerning births and abortions among all women aged 15–19 years residing in Denmark, Finland, Iceland, Norway and Sweden ... -
Factors Associated with Cesarean Section among Primiparous Women in Georgia: A Registry-based Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-21)Cesarean section rates remain high in Georgia. As a cesarean section in the first pregnancy generally lead to a cesarean section in subsequent pregnancies, primiparous women should be targeted for prevention strategies. The aim of the study was to assess factors associated with cesarean section among primiparous women. The study comprised 17,065 primiparous women with singleton, cephalic deliveries ... -
Hormonal IUD is the major hormonal contraceptive method used among women aged 40 –49 years: Data from the 2015 –16 Tromsø Study, Norw
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-23)Objective - This study aims to investigate hormonal contraceptive (HC) use and user characteristics in women aged 40–49 years in Norway, as little is known on use of HCs in this age segment.<p> <p>Material and methods - This prevalence study included 2296 women aged 40–49 years who participated in the 2015–16 Tromsø Study, which collected self-reported sociodemographic information and data from ... -
HPV mRNA is more specific than HPV DNA in triage of women with minor cervical lesions
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014-11-18)311 women were scheduled for triage of minor cervical lesions (ASC-US / LSIL). 30 women (9.6%) had ASC-H/HSIL cytology at triage and 281 women (90.4%) had ASC-US/LSIL or normal cytology. The HPV DNA test was positive in 92 (32.7%) of 281 instances, and 37 (13.2%) were mRNA positive. Of the 132 women with repeated ASC-US/LSIL, we received biopsies from 97.0% (65/67) of the DNA-positive and 92.9% ... -
HPV mRNA test in primry screening of women 20-34 years
(Conference object; Konferansebidrag, 2011) -
HPV mRNA testing in triage of women with ASC-US cytology may reduce the time for CIN2+ diagnosis compared with repeat cytology.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Background: In delayed HPV triage women with atypical squamous cells of uncertain significance (ASC-US) cytology are retested after 6-12 months in order to decide whether they should be referred for colposcopy, further follow-up cytology or routine screening in three years. Triage using a specific HPV E6/E7 mRNA test may reduce referrals for colposcopy of women with ASC-US cytology compared to HPV ... -
HPV mRNA testing is more specific than HPV DNA testing in triage of women with minor cervial lesions
(Conference object; Konferansebidrag, 2013)In Norway, repeat cytology and HPV testing is used in delayed triage of women with minor cytological lesions. Repeat cytology, HPV DNA testing (Roche Cobas 4800), and HPV mRNA testing (NorChip PreTect HPV-Proofer) were used to follow up 575 women aged 25–69 years with ASCUS / LSIL in primary screening. A total of 206 women (35.8%) were DNA+ and 107 (18.6%) were mRNA+. Repeated ASC-US / LSIL was found ... -
HPV types in cervical cancer tissue in South Africa: A head-to-head comparison by mRNA and DNA tests
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-01)<p>Accurate identification of human papillomavirus (HPV)-types in cervical cancer tissue may be important for tailoring tests for primary screening and types to be included in a vaccine. The aim of this study was to compare test-performance of a 45-type HPV deoxyribonucleic acid (DNA)-test with a 9-type HPV messenger ribonucleic acid (mRNA)-test in cervical cancer tissues. <p>In a case-series design ... -
The impact of antenatal care utilization on admissions to neonatal intensive care units and perinatal mortality in Georgia
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-02)<i>Introduction</i> - Appropriate antenatal care (ANC) utilization has direct, significant effects on perinatal mortality (PM). Georgia has one of the highest PM rates (11.7 per 1000 births) in Europe and launched a more intensive ANC programme in 2018.<p> <p><i>Aim</i> - To evaluate the associations between the Adequacy of Prenatal Care Utilization (APNCU) index and neonatal intensive care unit ... -
Incidence and Causes of Perinatal Mortality in Georgia
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-28)Georgia has one of the highest perinatal mortality rates (i.e., stillbirths and early neonatal deaths combined) in Europe. The Georgian Birth Registry was started in 2016 to provide data for preventive measures of maternal and child health. In this study, we aim to determine the incidence of perinatal mortality, assess the distribution of stillbirths and early neonatal deaths, and to determine the ...
